Download Fluorescence In Situ Hybridization (FISH) - Application by Thomas Liehr PDF

By Thomas Liehr

This booklet is a distinct resource of knowledge at the current kingdom of the interesting box of molecular cytogenetics and the way it may be utilized in examine and diagnostics. the fundamental suggestions of fluorescence in situ hybridization and primed in situ hybridization (PRINS) are defined, the a number of methods and probe units which are now to be had for those innovations are defined, and purposes of them are offered in 36 chapters by means of authors from ten diverse nations world wide. The ebook not just presents the reader with easy and history wisdom at the subject, but in addition supplies special protocols that express how molecular cytogenetics is at the moment played by means of experts during this box. The FISH program consultant first and foremost offers an outline of the (historical) improvement of molecular cytogenetics, its easy systems, the gear required, and probe new release. The ebook then describes counsel and methods for making diversified tissues to be had for molecular cytogenetic reports. those are by means of chapters on a variety of multicolor FISH probe units, their availability, and their pot- tial to be used together with different methods. the prospective functions which are proven surround the characterization of marker chromosomes, cryptic cytogenetic aberrations and epigenetic adjustments in people through interphase and metaphase cyto- netics, reviews of nuclear structure, in addition to the applying of molecular cytogenetics to zoology, botany and microbiology.

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