Download Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH): The by Michael A. Sirover PDF

By Michael A. Sirover

Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH): The necessary Moonlighting Protein in common mobilephone functionality and in Human Disease examines the biochemical protein interactions of the multi-dimensional protein GAPDH, additional contemplating the regulatory mechanisms by which cells keep watch over their useful variety.

This protein’s diversified actions variety from nuclear tRNA export and the upkeep of genomic integrity, to cytoplasmic post-transcriptional regulate of gene expression and receptor mediated telephone signaling, to membrane facilitation of iron metabolism, trafficking and fusion.

This e-book may be of serious curiosity to uncomplicated scientists, clinicians and scholars, together with molecular and cellphone biologists, immunologists, pathologists and scientific researchers who're drawn to the biochemistry of GAPDH in wellbeing and fitness and disease.

  • Contextualizes how GAPDH is used by cells in vivo
  • Provides distinct perception into GAPDH post-translational adjustments, together with useful range and its subcellular localization
  • Includes forward-thinking exposition on difficult subject matters, reminiscent of the exploration of the way GAPDG plays services, the way it comes to a decision the place it's going to be current and considered necessary structural requirements

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