Download Telomerases: Chemistry, Biology and Clinical Applications by Neal Lue,Chantal Autexier PDF

By Neal Lue,Chantal Autexier

This e-book is a complete and updated evaluation and assessment of the modern prestige of telomerase research.  Chapters during this quantity conceal the elemental constitution, mechanisms, and variety of the fundamental and regulatory subunits of telomerase.  different issues contain telomerase biogenesis, transcriptional and post-translational law, off-telomere features of telomerase and the position of telomerase in mobile senescence, getting older and melanoma. Its courting to retrotransposons, a category of cellular genetic parts that stocks similarities with telomerase and serves as telomeres in chosen organisms, also are reviewed.

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